An academic friend requested an actual Bibliography Page.  I decided he had a point.  I have a lot more to add to this page, so come back…

Good Books and Films

Dr. Richard Johnson, “The Fat Switch”  Really good comparative biology in the first part of the book.  Dr. Johnson’s lab is doing fundamental work on the mechanisms of sugar toxicity.

Dr. Robert Lustig, “Fat Chance”  This introduces the issue of sugar toxicity decently.  Dr. Lustig is a pediatric endocrinologist.  The beginning of most chapters has a bit of case information that illustrates the chapter’s topic well.

Gary Taubes,  “Good Calories, Bad Calories”  Gary’s exhaustive analysis.

Gary Taubes, “Why We Get Fat” — simplest introduction to the basic biology for most readers.

Drs. Jeff Volek and Steve Phinney, “The Art and Science of Low Carbohydrate Living“.  This is the best introduction to the biology and physiology of low carbohydrate nutrition, but not always the easiest to read if you don’t have a biological sciences background.

Drs. Jeff Volek and Steve Phinney, “The Art and Science of Low Carbohydrate Performance

Drs. Eric Westman, Jeff Volek, and Steve Phinney, “New Atkins for a New You” — best how-to for an Atkins-style low carb diet.

Jimmy Moore and Dr. Eric Westman, Cholesterol Clarity — what does cholesterol mean?

Jimmy Moore and Dr. Eric Westman, Keto Clarity — I learned more about keto-adaptation, despite the other books I’ve already read.

The documentary Fed Up, produced by Stephanie Soechtig, narrated by Katie Couric.  A decent problem statement, with some insights into the misguided public policy in the U.S. that has driven the obesity epidemic since the publication of the document Dietary Goals for the the United States in 1977.

Damon Gameau created the movie That Sugar Film and it’s companion That Sugar Book (see the website).  Damon starting out eating a very good diet with relatively low carbohydrate content, all from good sources, and 50% of calories from health fats.  He shifted to conventional “healthy” high carb/sugar diet for 60 days while medical professionals measured the results.  They were generally amazed at how quickly his health measures deteriorated.

Thomas Seyfried’s Cancer as a Metabolic Disease.  This is a very technical discussion of the underlying cause of cancer–mitochondrial malfunction.  Very important work, but heavy going.

Pat Shipman’s The Invaders.  This is a book of anthropology and paleoecology that details the timing of Homo Sapiens spread across Eurasia and the effects, including the extinction of Neanderthals.  She proposes we partnered with wolf-dogs.  This is very useful for establishing context relative our current world.

Chris McDougall, Born to Run — this isn’t a nutrition book either.  It has significant flaws, but it does introduce the concept of our evolutionary past as persistence hunters.

Dr. Richard Jacoby’s Sugar Crush— This book explains neural damage due to sugar.  It’s informative and has a good diet section.

Nicolette Hahn Niman’s Defending Beef— A fascinating integration of applied ecology and nutrition.  This book ranks with Gary Taubes’ work for making me think differently.

Worthwhile Lectures

Dr. Robert Lustig, “Sugar, The Bitter Truth

Dr. Jeff Volek, “New Paradigms for Carbohydrate Nutrition for Athletes

Popular Press

The Sugar Conspiracy by Ian Leslie.

Primary Literature– I try to have a dual link system.  The article title is typically linked to a PDF on my Google Drive.  The second link, if it’s there, points to the URL of the journal where the article appeared.

Lustig and associates–

Basu, Yoffe, Hills, Lustig, The Relationship of Sugar to Population-Level Diabetes Prevalence, PLOS ONE Feb. 2013, Vol 8, Issue 2, e57873

Bremer, Mietus-Snyder, Lustig, Toward a Unifying Hypothesis of Metabolic Syndrome, Pediatrics, Feb. 20 2012, 2011-2912

Lustig, Schmidt, Brindis, The Toxic Truth About Sugar, Nature, Feb. 2, 2012, Vol. 482

Lustig, Fructose: Metabolic, Hedonistic, and Societal Parallels with Ethanol, J Am Diet Assoc. 2010:110: 1307-1321

Lim, Mietus-Snyder, Valente, Scharz, Lustig, The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome, Nat. Rev. Gastroenterol. Hepatol. April 6, 2010, Vol 7 251-264

Johnson and associates–

Kanbay, Jensen, Solak, Le, Roncal-Jimenez, Rivard, Lanaspa, Nakagawa, Johnson, Uric acid in metabolic syndrome: From an innocent bystander to a central player, Eur J Intern Med. 2016 April; 29: 3-8. dos:10.1016/j.ejim.2015.11.026

Kratzera, Lanaspac, Murphyd, Cicerchic, Gravese, Tiptonf, Ortlund, Johnsonc, Gaucher, Evolutionary history and metabolic insights of ancient mammalian uricases, Proceedings of the National Academy of Sciences, March 11, 2014, Vol. 111, no. 10, 3763-3768:

Johnson, Nakagawa, Sanchez-Lozada, Shaftiu, Sundaram, Le, Ishimoto, Sautin, Lanaspa, Sugar, Uric Acid, and the Etiology of Diabetes and Obesity, Oct. 2013, Diabetes 62:3307-3315.

Lanaspa, Ishimoto, […], and Johnson, Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome, August 2013, NATURE COMMUNICATIONS | DOI: 10.1038/ncomms3434

Johnson, Stenvinkel, Martin, Jani, Sanchez-Lozada, Hill, Lanaspia, Redefining Metabolic Syndrome as a Fat Storage Condition Based on Studies of Comparative Physiology, Obesity (Silver Spring), 2013 April: 21(4): 659-664

Lanaspa et al, Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress, Journal of Biological Chemistry, 2012 Nov 23;287(48):40732-44,  doi: 10.1074/jbc.M112.399899

Lanaspa, Sanchez-Lozada, Cicerchi, Li, Roncal-Jimenez, Ishimoto, Le, Garcia, Thomas, Rivard, Andres-Hernando, Hunter, Schreiner, Rodriquez-Iturbe, Sautin, Johnson, Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver, PLOS One, Oct. 2012, Vol. 7, Issue 10, e47948

Mehdi, Elias, Johnson, Wright, Contribution of uric acid to cancer risk, recurrence, mortality, Clin Trans Med, Aug. 15, 2012 1:1610.1186/2001-1326-1-16

Sautin, Johnson, Uric Acid: The Oxidant-Antioxidant Paradox, Nucleosides Nucleotides Nucleic Acids 2008, June: 27(6): 608-619. doi: 10.1080/15257770802138558

Johnson, Perez-Pozo, Sautin, Manitius, Sanchez-Lozada, Feig, Shafiu, Segal, Glasssock, Shimada, Roncal, Nakagawa, Hypothesis: Could Excessive Fructose Intake and Uric Acid Cause Type 2 Diabetes?, Endocrine Reviews 2009, 30(1):96-116, doi:10.1210/er.2008-0033

Saturated Fats–

Harcombe Z,Baker JS, Cooper SM, et al. Evidence from randomised controlled trials did not support the introduction of dietary fat guidelines in 1977 and 1983: a systematic review and meta-analysis. Open Heart 2015;2:e000196. doi:10.1136/openhrt-2014- 000196

Volk BM, Kunces LJ, Freidenreich DJ, Kupchak BR, Saenz C, Artistizabal JC, et al. (2014) Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome. PLoS ONE 9(11): e113605. doi:10.1371/journal.pone.0113605

Ketogenic Diets– 

Feinman, et al, Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base, Nutrition 31 (2015) 1-13.

Paoli, Rubini, Volek, Grimaldi, Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets, European J of Clin Nutr (2013) 67, 789-796

Ruskin, Svedova, Cote, Sandau, Rho, Kawamura, Bolson, Masino, Ketogenic Diet Improves Core Symptoms of Autism on BTBR Mice, PLOS One, June 2013, Vol 8, Issue 6, e65021

Stafstrom, Rho, The ketogenic diet as a treatment paradigm of diverse neurological disorders, Frontiers in Pharmacology, April 2012, Vol 3,  Article 59

Badman, Kennedy, Adams, Pisslos, Maratos-Flier, A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss, Am J Physiology Endocrinol Metab. 2009 Nov.; 297(5): E1197-E1204

Westman, Yancy, Mavropoulos, Marquat, McDuffie, The effect of a low-carbohydrate, ketogenic diet versus a low glycemic index diet on glycemic control in type 2 diabetes, Nutrition & Metabolism 2008, 5:36, dii:10.1186/1743-7075-5-36 (

Volek, Phinney, Forsythe, Quann, Wood, Puglisi, Kraemer, Bibus, Fernandez, Feinman, Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet, Lipids, Nov. 2008, DOI 10.1007/s11745-008-3274-2

Volek, Fernandez, Feinman, Phinney, Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome, Prog Lipid Res (2008), doi:10.1016/jplipres.2008.02.003

Westman, Feinman, Mavropoulos, Vernon, Volek, Wortman, Yancy, Phinney, Low-carbohydrate nutrition and metabolism, Am J Clin Nutr 2007;86;276-84

Kennedy, Pissios, Otu, Xue, Asakura, Furukawa, Marino, Liu, Kahn, Libermann, Maratos-Flier, A high-fat, ketogenic diet induces a unique metabolic state in mice, Am J Physiol Endocrinol Metab 292; E1724-E1739, 2007.

Gasior, Rogawski, Hartman, Neuroprotective and disease-modifying effects of the ketogenic diet, Behav. Pharmacol. 2006 Sep: 17(5-6):431-439

Manninen, Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood “Villains” of Human Metabolism, Journal of the International Society of Sports Nutrition, 2004 1(2):7-11 (

Exercise Physiology–

Noakes, Volek, Phinney, Low-carbohydrate diets for athletes: what evidence?Br J Sports Med 2014;48:1077–1078. doi:10.1136/bjsports-2014-093824


Wang, Xu, […], and Sun, Increased Risk of Cancer in relation to Gout: A Review of Three Prospective Cohort Studies with 50,358 Subjects, Mediators of Inflammation, 2015:

Seyfried, Flores, […], and S’Agostino, Cancer as a metabolic disease: implications for novel therapeuticsCarcinogenesis. 2014 Mar; 35(3): 515–527. 

Fini, Elias, […], and Wright. Contribution of uric acid to cancer risk, recurrence, and mortality,Clinical and Translational Medicine. 2012;1:16. doi:10.1186/2001-1326-1-16.

Klement, Kammerer, Is there a role for carbohydrate restriction in the treatment and prevention of cancer?, Nutrition and Metabolism 2011, 8:75 (

Seyfried and Shelton, Cancer as a metabolic disease, Nutrition & Metabolism 2010, 7:7,


Jonasson, Guldbrand, Lundberg, and Nystrom, Advice to follow a low-carbohydrate diet has a favourable impact on low-grade inflammation in type 2 diabetes compared with advice to follow a low-fat diet, Ann Med. 2014 May: 46(3): 182-187.

Boos, Anderson, Lip, Is atrial fibrillation an inflammatory disorder? European Heart Journal Nov. 8, 2005, Vol. 27, Issue 2, Pp. 136-149 DOI: 136-149

Human Evolution–

Sayer, Lovejoy, Blood, bulbs, and bunodonts: on evolutionary ecology and the diets of Ardipithecus, Australopithecus, and early HomoQ Rev Biol. 2014 Dec; 89(4): 319–357. 

Bozek et. al., Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness, PLOS|Biology May 27, 2014, doi:10.1371/journal.pbio.1001871

Werdelin, Lewis, Temporal Change in Functional Richness and Evenness in the Eastern Africa Plio-Pleistocene Carnivoran Guild, PLoS ONE (2013) 8(3): e57944. dii:10.1371/journal.pone.0057944

Roach, Venkadesan, Rainbow, Lieberman, Elastic energy storage in the shoulder and the evolution of high-speed throwing in Homo,Nature, 2013 June 27; 498(7455:483-486. doi:10.1038/nature12267

Lieberman, Bramble, The Evolution of Marathon Running, Sports Med 2007; 37(4-5) 288-290

Bramble, Lieberman, Endurance running and the evolution of Homo, Nature; Nov. 18, 2004; 432, 7015; ProQuest Science Journals

Macular Degeneration–

Schleicher, Weikel, Garber, Taylor, Diminishing Risk for Age-Related Macular Degeneration with Nutrition: A Current View, Nutrients 2013, 5, 2405-2456; doi: 10.3390/nu5072405

Kaushik, Wang, Flood, Tan, Barclay, Wong, Brand-Miller, Mitchell, Dietary glycemic index and the risk of age-related macular degeneration, Am J Clin Nutr 2008:88:1104-10

Chiu, Milton, Klein, Gensler, Taylor, Dietary carbohydrate and the progression of age-related macular degeneration: a prospective study from the Age-Related Eye Disease Study, Am J Clin Nutr 2007;86:1210-8


Gray, Mitochondrial Evolution, Cold Spring Harbor Perspectives in Biology, 2012, Sept. 4(9): a0011403.  PDF

Sugar Toxicity–

Malhorta, Noakes, Phinney, It’s time to bust the myth of physical inactivity and obesity: you cannot outrun a bad diet.  British Journal of Sports Medicine, April 22, 2015, Br J Sports Med doi:10.1136/bjsports-2015-094911

de la Monte, Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimer’s Disease, Current Alzheimer Research, 2012, 9, 35-66

Roberts, Roberts, Geda, Cha, Pankratz, O’Connor, Knopman, Peterson, Relative Intake of Macronutrients Impacts Risk of Mild Cognitive Impairment or dementia, J Alzhiemers Dis. 2012 January 1; 32(20): 329-339. doi:103233/JAD-2012-120862

Stanhope, Schwarz […], and Havel, Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humansJ Clin Invest. 2009 May 1; 119(5): 1322–1334. 

de la Monte, Wands, Alzheimer’s Disease is Type 3 Diabetes–Evidence Reviewed, J Diabetes Sci Technol 2008;2(6);1101-1113

Uric Acid–

Billie, Dotty, Katz, Velazquez, Review of Hyperuricemia as New Marker for Metabolic Syndrome. ISRN Rheumatology, Volume 2014 (2014), Article ID 852954, 7 pages,

Ford, Li, Cook, Choi, Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents.Circulation,2007; 115: 2526-2532

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